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Data from the National Health Insurance Service in Korea was used to evaluate if the use of statins had any effect on the risk of developing HCC. More than half a million individuals over the age of forty were randomly sampled from over 5 million persons who...

The BREATHER study was a non-inferiority trial of efavirenz based antiretroviral treatment 5 days a week compared to daily treatment in children, adolescents and young adults. After 48 weeks the 5 days therapy was shown to be non-inferior to daily therapy. The study...

107 Spanish HIV-positive patients on antiretroviral therapy were evaluated in a cross-sectional study for risk factors for low BMD. BMD of lumbar spine and femoral neck was measured with dual-energy X-ray absorptiometry and a multivariate analysis was performed...

The Data collection on Adverse Events of Anti-HIV Drugs (D:A:D) study consists of 11 different cohorts. In the present study 35,711 HIV-positive individuals were included and followed from 2009 until 2016 or until 6 months after a cardiovascular event. During a...

In fourteen sites in Sub-Saharan Africa and India HIV-infected pregnant women with CD4 > 350 or country-specific thresholds for antiretroviral therapy (ART) were included in a trial comparing ART to the mother to nevirapine to the infant to prevent transmission...

40 HIV-infected patients on abacavir-containing treatment with platelet hyperreactivity participated in a randomized, placebo-controlled cross-over study of aspirin in combination with abacavir. Platelet hyperreactivity was defined by a score based on laboratory...

In a systematic review of 358 datasets representing 56,044 adult patients in 63 countries the pretreatment drug resistance to non-nucleoside reverse transcriptase inhibitors (NNRTIs) was estimated. NNRTI resistance was more prevalent in more recent studies compared...

541 HIV-positive treatment naïve patients started treatment with a rilpivirine containing regimen. Next generation sequencing (NGS) was performed to identify minority resistant variants to nucleoside reverse transcriptase inhibitors (NRTIs) and non-nucleoside...

Two prospective studies of treatment of acute hepatitis C recruited patients in 17 Dutch HIV-centers. The centers include 76 % of the HIV positive MSM population in the Netherlands. In 2015, direct-acting antivirals (DAAs) for HCV became available to all Dutch HCV-...

Eleven randomized trials comparing TAF and TDF for HIV and hepatitis B were analyzed for efficacy, bone toxicity and renal events. A predefined sub-group analysis compared regimens with TAF and TDF with or without boosting with ritonavir (RTV) or cobicistat (COBI)....

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