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A meta-analysis of studies of hepatitis C assessing all-cause mortality in SVR and non SVR was performed through a search of Medline and EMBASE from 1990 to November 2014. 31 studies were identified with...

In the ENCORE trial treatment naïve HIV positive patients with CD4 cells between 50 and 500 were randomized to 400 or 600 mg of efavirenz together with fixed dose combination of tenofovir and emtricitabine....

400 Ugandan HIV patients who were initiating or who had been or antiretroviral therapy for less than 6 month were randomized to supplementation with multivitamins or placebo. ...

2491 HBsAg positive individuals with negative e-antigen were followed for a median of 10.1 years. They all had genotype B or C. A scoring system based on age, HBV-DNA levels and HBsAg titer was constructed. Clearance was defined as two negative tests for HBsAg one...

A total of 1175 patients from two different studies of patients with e-antigen positive hepatitis B were retrospectively analyzed for predictors of liver fibrosis. All patients were Asians and had genotype C or D and all had undergone liver biopsy. Baseline HBsAg...

In a similar study design 286 HIV positive patients from 30 hospitals in Spain were randomized 1:1 to triple therapy with atazanavir/ together with two NRTIs or dual therapy with atazanavir/r together with lamivudine. Patients with stable antiretroviral therapy and...

250 HIV-positive patients from 32 HIV units in Spain and France were included in a simplification study. Eligible patients were treated with lopinavir/r and 2 NRTI:s and had viral load less than 50 copies/mL for at least 6 months. Patients were randomized 1:1 to...

In a large retrospective non randomized cohort study the composite endpoint of tuberculosis (TB) and death was compared in HIV-positive patients who received both ART and Isoniazid Preventive Therapy (IPT) compared to ART only. The cohort included patients with HIV...

178 HIV-positive individuals with at least 200 CD4 cells who were non responders to 2-4 doses of Hepatitis B vaccination were randomized to receive revaccination with 3 doses of standard (20 μg) or double dose (40 μg) vaccine. Before randomization all participants...

In a Korean study 90 patients with entecavir (ETV) resistant Hepatitis B were randomized to tenofovir disoproxil fumarate (TDF) as monotherapy or the combination of TDF and ETV. All patients had at least one resistance-associated mutation and detectable HBV-DNA at...

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