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In a study from Australia/New Zealand 19 patients with recent hepatitis C infection were treated with sofosbuvir and weight based ribavirin for 6 weeks. Recent hepatitis C was defined as a duration of infection < 12 months. 14 of the participants were
HIV-...

In a German study of acute hepatitis C treatment with fixed dose LDV/SOF was given for 6 weeks. Acute HCV infection was defined as a known seroconversion to HCV within 4 months or known or suspected exposure to HCV within four months and ALT-level at least ten times...

In an earlier report it has been suggested that the concomitant use of PPI with LDV/SOF may lead to decreased rates of sustained viral response (SVR). A real life observational study of 1979 patients treated with LDV/SOF was performed to evaluate the effect of PPI...

YKL-40 is a biomarker of microglial cell activation. In a cross-sectional study the level of YKL-40 was measured in cerebrospinal fluid in two groups of HIV positive patients before initiation of therapy. The first group consisted of patients with acute infection (n...

A retrospective cross-sectional study of 1018 patients with non-alcoholic fatty liver disease (n=155), hepatitis C (n=378) and hepatitis B (n=485) showed that coffee intake is associated with lower liver stiffness. Tea and coffee intake was assessed and transient...

In the large START study immediate versus delayed initiation of antiretroviral therapy was compared in patients with CD4 counts above 500 cells/μL. Patients were randomized to immediate therapy or deferred therapy until the CD4 count was lower than 350. Immediate...

In two Chinese provinces children of Hepatitis B surface antigen positive/hepatitis E antigen negative (HBsAg+/HBeAg-) mothers were vaccinated against hepatitis B with or without Hepatitis B immune globulin (HBIG). This was an observational non-randomized study but...

In a needle exchange program in southern Sweden, all participants who were hepatitis B susceptible were offered a standard three doses vaccination schedule with a commercially available vaccine. Those who had no serological response (anti-HBs < 10 mIU/mL) were...

575 treatment naïve HIV positive women from 80 centers in 11 countries were enrolled in a randomized double blind placebo controlled study of two different regimens for HIV. An estimated creatinine clearance of 70 ml/min or higher was a requirement to be included....

A cohort of 5984 HIV/HCV coinfected individuals from the Veterans Affairs HIV and HCV Clinical Case Registries 1999-2010 were evaluated for factors influencing liver cirrhosis development. Statin use was measured as percentage time with active prescription. The mean...

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