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Incidence and prevalence of diabetes mellitus was investigated in the large Italian ICONA cohort. For incidence, 6,505 participants were followed for a total of 38,062 years of follow-up. The incidence was compared in three groups: Hepatitis C antibody (HCV-ab)...

22 treatment-naïve patients with early HIV infection were treated with boosted lopinavir and emtricitabine/tenofovir disoproxil fumarate and randomized to either placebo or intensified therapy with raltegravir and maraviroc. Early HIV infection was defined as...

In a randomized open-label study the viral decay in semen was compared between three different antiretroviral regimens. Treatment-naïve HIV-positive men with plasma viral loads between 1,000 and 100,000 copies/ml and seminal plasma level > 1,000 were included in...

More than 20 000 Taiwanese adult patients who were diagnosed with HIV from 2000 until 2012 were followed for incident psoriasis for a median time of 5 years. A control group of more than 80,000 persons was matched for age and sex. During the follow up 252 cases of...

192 Korean patients with chronic hepatitis B with multiple drug resistance mutations against lamivudine (LAM), entecavir (ETV) and/or adefovir (ADF) were randomized to monotherapy with TDF or combination therapy with TDF and ETV. The primary endpoint was the...

10 patients with sickle-cell anemia and hepatitis C genotype 1 or 4 were treated with ledipasvir/sofosbuvir. One patient with cirrhosis received 24 weeks of therapy. The remaining 9 patients without cirrhosis were treated for 12 weeks. Only one patient did not...

GSK3532795 is a second generation maturation inhibitor. Its mode of action is inhibition of protease mediated cleavage between capsid protein p 24 and spacer protein -1 in the Gag polyprotein resulting in immature noninfectious viral particles. A

The risk of biopsy confirmed cervical high grade squamous intraepithelial neoplasia or worse (bHSIL+) in HIV-positive women in the Women´s Interagency HIV Study was calculated and compared to specific management strategies in the general population. 2,423 HIV-...

In the prospective Swiss HIV Cohort study all treatment naïve patients who initiated antiretroviral therapy with raltegravir or dolutegravir between 2006 and 2015 were evaluated for treatment modifications during the first year of treatment. 2,091 patients started...

In a French cohort 2,287 patients that had less than 200 in CD4 cell count and who started antiretroviral therapy (ART) between 2010 and 2015 were identified. Data were prospectively collected. 398 patients started therapy with Integrase inhibitors (INSTI) and 1,889...

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