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Patients from 18 European and North American HIV cohorts were included in an analyses of the mortality during the first three years after initiation of antiretroviral therapy (ART). Four calendar periods were compared;1996-99, 2000-03, 2004-07 and 2008-10. The study...

Data from several major prospective studies was used to compare dynamic monitoring strategies for CD4 counts. 47,635 patients were included in the study from year 2000 until 2015. Three different CD4 thresholds of 200, 350 and 500 cells/mL were used. For each...

In an observational Thai study of HV positive patients with less than 100 CD4 cells/μL who initiated antiretroviral therapy, the effect of prophylactic fluconazole was evaluated. All patients had a negative cryptococcal serum antigen test at inclusion and no history...

252 HIV positive patients on antiretroviral therapy with dyslipidemia were randomized to once daily treatment with either pitavastatin 4 mg daily or pravastatin 40 mg. The study was double dummy double blind. Both statins have favorable pharmacokinetic profiles in...

In a prospective cohort study from Japan hepatitis B inactive carriers were followed from 2011 to 2015. The definition of an inactive carrier was ALT below 31 u/L (0.53μkat/L) and HBV-DNA below 4 log copies/mL and negative HBeAg. Baseline blood tests and...

In the UK CHIC cohort study 1430 patients who switched from either atazanavir or lopinavir containing antiretroviral treatment combinations to darunavir were evaluated for changes in kidney function. At least 6 months of therapy pre and post switch was required for...

In the Swiss Human Immunodeficiency Virus Cohort all patients with HIV and hepatitis B coinfection were tested for delta hepatitis. Patients with HDV-RNA > 300 copies/mL at initiation of tenofovir (TDF) therapy and who had a follow up sample after at least one...

64 HIV-positive patients with early syphilis were randomized to single dose versus 3 dose regimen of 2.4 million units of intramuscular benzathine penicillin G. Early syphilis was defined as primary, secondary or early latent syphilis. Syphilis diagnosis was based...

1292 coinfected Spanish patients were included in a retrospective study of the prognostic value of TE. All patients had undergone at least one examination with TE after it was introduced as a routine procedure to evaluate liver fibrosis in coinfected patients2006....

Data from a cotrimoxazole cessation study in Ugandan HIV-positive adults was used to evaluate the effect of antiretroviral therapy on the incidence of malaria. Patients with more than 250 CD4+ cells/μL were randomized to receive placebo or cotrimoxazole....

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